Thursday, October 14, 2010

Cycle was canceled

FUCK!!!!

Yup. That's the nicest thing I've got to say about that. We got the testing results back this afternoon. And it's been confirmed - I'm a genetic cesspool.

Out of the 8 that made it to biopsy for testing...

3 of the embryos had no results. The cell sample they sent had no nucleus to test.

1 girl had Trisomy 21 (Down's Syndrome)

1 girl had Trisomy 13

2 girls were missing a chromosome (Turner's Syndrome)

There was only one normal embryo - and it was a boy - with a 1 in 4 chance of fatality due to the Bilateral Renal Agenesis.

We're freezing the unknowns and the boy. They may be able to test the unknowns in the future (not in the next few weeks, but possible in a matter of months).

So... we're going to try to take out a loan and try one more cycle retrieving. If the genetics are still this crappy, well then we'll be working on saving up money for lots of nice vacations.

I'm going to spend the next few days licking my wounds, but hopefully back in the saddle in a few weeks.

Tuesday, October 12, 2010

The count down is on!

I heard from the doctor's office yesterday and final count was 18 eggs, 16 were mature, 10 fertilized!

I'm excited, but trying not to get too excited - it gives us 10 fertilized eggs to work with... but... we're also doing gender selection. Please know that we're not doing gender selection for vanity reasons, we've lost two boys in the last 5 years due to a genetic condition that is 3 times more fatal in boys than girls. Unfortunately, they haven't isolated the gene that causes the condition (Bilateral Renal Agenesis)- but the odds of fatality with another male are about 1 in 4, the odds of fatality with a girl are 1 in 12. I know it's a tricky subject, so I appreciate your support, but ask that you keep any ethical concerns to yourself. Our doctors have agreed it is a valid medical reason and meets all ethical guidelines. Phew, now I've put that out there I feel a little better!

Transfer is scheduled for Friday. We're having testing preimplantation genetic testing done to screen for major chromosomal disorders and gender selection... and we're keeping our fingers crossed that we have enough good quality embryos - We're looking to transfer 2. I've gotten pregnant pretty easily on IUI with Clomid (pregnant 2 out of 3 tries), so I don't really want to take the chance with triplets. Based on my age they recommend 2-3 eggs embryos to transfer, so we're erring on the side of caution with only 2. Who knows? Maybe we'll have enough to do a second transfer if this cycle doesn't work.

Last night was our first progesterone shot (the one intramuscular shot that the baron has to give me)... and it was interesting. I bled a little from the shot, and guess who almost passed out? Hint - it wasn't me!

I'm doing good, a little cramping, trying to hydrate as much as possible with electrolytes to avoid OHSS, but I'm generally uncomfortable. There's a good chance of my working from home if I don't stop with the bloating soon. Yup, I'm not above calling in "fat and nothing to wear" to work!

Sunday, October 10, 2010

Retrieval Update

Today's blog is brought to you by the number 18!!!! That's not a typo. Eighteen. Retrieval went really well, they were able to retrieve 18 eggs. I'm still a little dopey from the anesthesia, so this may be a little disjointed, but it went well. Tomorrow we should find out how many fertilized, and Friday we'll do the transfer.

On a strange karma / good omen note... One of Dad's friends from India posted pictures of him this morning. How weird is that? It was such perfect timing, it's like he was watching over us today.

Headed to the couch to go back to sleep, but wanted to share the good day...

Tuesday, October 5, 2010

Holy Follies!!!

I couldn't wait until I get home to share... I have NINE little follicles ready to go! They said I needed at least 4 that measured over 1.0cm to continue on to retrieval... and I've got 4 that are almost at 1.5, another 4 are over 1.0, and 1 little guy that's at .96

It looks like I'm responding very well to the meds and egg retrieval may take place this weekend.

I'm scared to even say it...but I'm feeling really good about the whole thing.

Monday, October 4, 2010

Just a Fly-by

Quick update for the inquiring minds...

Lupron suppression part of the cycle sucked. I was depressed, "flat", and it was a general preview of menopause. Blech.

I'm on all the stimulation meds now and going for blood work and testing every other day. Compared to the suppression meds... stim meds rock! Yeah, I look like a pincushion, I'm bruised all over my stomach from the injections, my arms look those of a junkie, I'm bloated beyond belief, I'm exhausted - but mentally/emotionally - I feel great!

Things of note with the shots:
- They give you a drawing where you're supposed to inject... luckily, I have a huge fat roll right there, no chance of missing the spot 2 inches below the belly button
- My arms really do look like a junkie's. I went for blood work yesterday, and they refused to take blood from the good arm because it's too bruised and they wanted it to have a few days to heal - but the "bad" arm has veins that always jump and collapse, so it looks twice as bad as the good arm after one blood draw
- The first night on all the stim meds took me an hour to figure out how to do all the shots, it's down to about 15 mins now
- I've only been on the stim meds since Thursday, and I'm really bloated. If my stomach expands too much more, I'm going to start calling in fat/nothing to wear to work

Tomorrow is the first appointment where they'll be able to see how many little follicles are growing, keep your fingers crossed! I'm having nightmares that there won't be enough eggs to do the retrieval and this will all be for naught, but there's no sense worrying about things that are out of my control.

Off to nap and stab myself a few more times. Hopefully this time next week I'll be scheduled for retrieval and down to just one shot a day. Right now I'm on 3, and I'm running out of space to inject that isn't already bruised.